Discover how the brain changes with age through research on brain aging and cognition.
Parkinson’s disease is often reduced, in the public imagination, to one striking image: a trembling hand. While memorable, that picture is profoundly incomplete. It obscures the reality of a complex, progressive neurological disorder that reaches far beyond tremor and gradually reshapes the person’s entire psychocorporeal functioning. Parkinson’s disease affects the brain’s motor circuits, but also…
In the public imagination, Alzheimer’s disease is often reduced to a simple problem of memory. Forgetting names, faces, dates, or appointments is treated as the defining feature. While this picture is partly true, it is also deeply incomplete. It hides the complexity of a neurodegenerative disorder that gradually disrupts the person as a whole. First…
In an Alzheimer’s care unit, a striking scene unfolds time and again. A person who no longer recognizes their loved ones, who struggles to find words or remains silent, suddenly begins to sing. The singing is not always accurate or entirely faithful, but the melody, the rhythm, and sometimes even the lyrics emerge with unsettling…
For decades, brain aging has been investigated mainly through hormonal, metabolic and inflammatory lenses. A recent discovery suggests that part of the answer may lie deeper, within the genome’s structural organisation itself. Researchers at the University of California San Francisco have shown that in females, the inactive X chromosome, normally silenced to prevent double gene…
Aging isn’t just about wrinkles or grey hair. It’s a much deeper transformation—one that quietly reshapes us from within, deep in the folds of our brain. Once regarded as an inevitable or marginal phenomenon, aging is now at the forefront of scientific and societal concerns. Thanks to medical advances and improved living conditions, we’re living…
Alzheimer’s disease remains one of the most formidable challenges in neurology, both in terms of its growing prevalence and the complexity of its underlying mechanisms. While amyloid plaques and tau tangles are well-established pathological markers, a fundamental question persists: why do certain brain regions deteriorate early, while others show remarkable resistance? This selective vulnerability and…
Preventing cognitive decline has become a major public health concern. As life expectancy increases, so do cases of dementia, pushing researchers to identify factors that could help protect the brain. Risk factors such as depression and anxiety are now well established. However, the potential protective effects of psychological wellbeing remain underexplored. Psychological wellbeing goes beyond…
Sitting for hours each day is no longer just a cardiovascular or metabolic health concern, it has become a serious warning sign for the brain. In a world where sitting has become the invisible norm, from the office chair to the driver’s seat, the couch to the screen, sedentary behavior is no longer a simple…
It is fascinating to consider that, just as a great civilization may crumble not due to an external disaster but because of internal flaws, the human brain, too, can collapse from within through the gradual erosion of its connections. Frontotemporal degeneration (FTD) presents this profound reality, where the very complexity that defines us can ultimately…